Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01270e Click here for additional data file.

نویسندگان

  • Y. R. Baker
  • J. T. Hodgkinson
  • B. I. Florea
  • E. Alza
  • W. R. J. D. Galloway
  • L. Grimm
  • S. M. Geddis
  • H. S. Overkleeft
  • M. Welch
  • D. R. Spring
چکیده

† Present address Y.R.B.: Department of Chemistry, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford OX1 3QZ, U.K. ‡ Present address J.T.H.: Department of Chemistry, University of Leicester, Leicester LE1 7RH, U. K. ¶ Present address E.A.: Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007, Tarragona, Spain

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منابع مشابه

Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes.

Many bacterial species, including the human pathogen Pseudomonas aeruginosa, employ a mechanism of intercellular communication known as quorum sensing (QS), which is mediated by signalling molecules termed autoinducers. The Pseudomonas Quinolone Signal (PQS) and 2-Heptyl-3H-4-Quinolone (HHQ) are autoinducers in P. aeruginosa, and they are considered important factors in the progress of infectio...

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Gold nanoparticle-based multivalent carbohydrate probes: selective photoaffinity labeling of carbohydrate-binding proteins† †Electronic supplementary information (ESI) available: The synthesis and characterization of the probes, PAL and their analysis. See DOI: 10.1039/c5sc03275j Click here for additional data file.

Multivalent carbohydrate photoaffinity probes were developed based on gold nanoparticles (AuNPs) to provide a streamlined approach toward identification of carbohydrate-binding proteins. By using AuNPs as scaffolds, a carbohydrate ligand and a photoreactive group could be readily assembled on a probe in a modular fashion, which greatly accelerated the process of optimizing the probe design. The...

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2017